People

Prof. Giorgio Berton   giorgio.berton_at_univr.it    Link

Giorgio Berton is Professor of General Pathology at the Faculty of Medicine, University of Verona. He has conducted research mainly in the field of cellular and molecular basis of innate defenses. The main topics covered by his research are: regulatory mechanisms and biochemical basis of NADPH oxidase, the main microbicidal system of phagocytic cells mechanisms of regulation of functions of granulocytes and monocytes/macrophages by cytokines signal transduction, and regulation of selective functions of granulocytes by adhesive molecules. In recent years he has focused his interests on the mechanisms of signal transduction by integrins in myelo-monocytic cells, and in particular on the role of the Src tyrosine kinase family. He published more than 100 scientific papers in international peered reviewed Journals including Journal of Cell Biology PNAS, Blood, Journal of Immunology, European Journal of Immunology, Journal of Leukocyte Biology, Journal of Cell Science, Journal of Biological Chemistry, Biochemical Journal, Journal of Cellular Physiology, Experimental Cell Research and has been referee of top international journals (Nature Cell Biology, Journal of Cell Biology, Journal of Immunology, Journal of Leukocyte Biology, European Journal of Immunology, Journal of Innate Immunity, Journal of Experimental Medicine, Blood, Journal of Cellular Physiology). He directed many scientific national and international projects. He is member of the Faculty of 1000 (F1000), and of important scientific associations and committees (Association of Cell Biology and Differentiation, Italian Society of Pathology, Italian Society of Immunology, Allergy and Clinical Immunology, Society for Leukocyte Biology, Scientific Advisory Board of the FFC - Foundation for Cystic Fibrosis, Editorial Board of Inflammation & Allergy-Drug Targets). He is among the “Top italian scientist” ( http:/www.topitalianscientists.org). Prof. Berton has been Director of the Department of the former Department of Pathology of the University of Verona and presently is member of the Directive Committee (CDA) of the University of Verona.



Dr. Manuele Bicego   manuele.bicego_at_univr.it    Link

Manuele Bicego received his Laurea degree in Computer Science from University of Verona (Italy) in 1999. From the same university, in 2003, he received the PhD degree in Computer Science. From 2004 to May 2005 he was a PostDoc Fellow at the University of Sassari (Italy). From June 2005 to September 2008 he was assistant professor (ricercatore) at the University of Sassari (Italy). With the same position he is now with the University of Verona (Italy), member of the VIPS (Vision, Image Processing and Sound) laboratory at the Computer Science Dept. From June 2009 to February 2011 he was also team leader and member of the PLUS (Pattern analysis, Learning and image Understanding Systems) lab at the Istituto Italiano di Tecnologia (IIT - Genova Italy). His research interests include statistical pattern recognition, mainly probabilistic models (GMM, HMM) and kernel machines (e.g. SVM), with application to video analysis, biometrics and, recently, bioinformatics. In this last context the main focus in on designing solutions for the analysis of "counting data" - namely data which express the level of presence of entities (e.g. gene expression data, or proteomics data) - using probabilistic graphical models like topic models. The main goal in his research is to devise highly interpretable solutions, being interpretability of methods and solutions the most stringent need in nowadays bioinformatics research. M. Bicego is author of several papers in the above subjects, published in international journals and conferences. Moreover he is an associate editor of ELCVIA and JoI journals. He has served as member of the scientific committee of different international conferences, and he is a reviewer for several international conferences and journals.



Giacomina Bruttomesso (Administrative assistant)   giacomina.bruttomesso_at_univr.it    Link

Giacomina Bruttomesso, called Anna, is administrative director of the department of Computer Science of the University of Verona. She got a master degree in Business Administration in 1992 at the University of Verona, where she worked in the administration of Medicine and Science departments, and in the former Scientific and Technological Department, before it was split in two departments (Biotechnology and Computer Science). She has a long experience in the management of research projects at Italian, European (since the 3rd European Framework Programme) and international levels. In her free time she enjoys farming and bee-keeping.



Prof. Mario Rosario Buffelli   mario.buffelli_at_univr.it    Link

Since 2006, Mario R. Buffelli is an Associate Professor of Physiology, at the Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona. He obtained his degree in Medicine and Surgery in 1987 and the PhD in Neuroscience in the 1995 under the supervision of Prof. Alberto Cangiano. During the PhD in Neuroscience he studied the trophic interactions between motoneurons and muscle fibers acquiring experience with electrophysiology (intracellular and extracellular recordings) and histochemical techniques. He became Assistant Professor in the 1998. He attended for two years (2000-2002) the laboratories of Joshua Sanes and Jeff Lichtman at the Washington University, Saint Louis (USA), Department of Anatomy and Neurobiology acquiring a broad experience in the application of imaging techniques and molecular biology to investigate, in vitro and in vivo, the phenomena of synapse elimination. He is author of several scientific articles regarding the role of activity in the development of nervous system. He is member of Italian Physiology Society, Italian Neuroscience Society and Society for Neuroscience. He is reviewer for several international scientific journals. At present, his research interests focus on the following topics: a) the molecular mechanisms underlying the axonal regeneration in the central and peripheral nervous system; b) molecular and structures that regulate the development of synapses in the peripheral and central nervous system; and c) synaptic plasticity in the nervous system in physiological and pathological conditions.



Dr. Alberto Castellini   alberto.castellini_at_univr.it    Link

Alberto Castellini (http://www.albertocastellini.tk) graduated in Computer Science in 2006 and earned his PhD in Computer Science, with a dissertation titled "Algorithms and Software for Biological MP Modeling by Statistical and Optimization Techniques", at the University of Verona. He is currently a postdoc research associate at the Center for BioMedical Computing in Verona.

His research interests focus on complex system modeling (simulation, prediction, etc.) by unconventional computation models, mathematical optimization by traditional end evolutionary strategies, and data analysis, with particular applications to systems biology and bioinformatics. Alberto's recent work mainly involved the development of biological models based on membrane computing, by means of statistical (e.g., regression, variable selection), machine learning (e.g., neural networks) and optimization (e.g., genetic algorithms) tools. He has also developed software tools for the majority of the research problems investigated (e.g., MetaPlab) and he is co-author of scientific papers on these subjects which gained the appreciation in international journals and congresses.

During his PhD Alberto visited for five months the Automated Scheduling Optimization and Planning (ASAP) group at the Nottingham University (UK), and for one month the Science of Complex Interaction Lab (SCI-LAB) at the Nagoya University (Japan). He also partecipated to courses and PhD schools on bioinformatics and bio-inspired calculus.

During his master degree he spent a period at the Heriott Watt University of Edinburgh, where he developed evolutionary optimization algorithms for applications in computer vision. After his graduation he did an internship at the Italian Space Agency where he developed software for the strategical analysis of data related to space products.



Francesco Maria Cirigliano   francesco.cirigliano_at_univr.it    Link

Francesco Maria Cirigliano is a computer technician (staff-head) responsible for systems and network administration at the University of Verona (Department of Computer Science). He has in charge the CBMC server, its network services, and the framework of web applications developed in the context of CBMC projects.



Dr. Gabriela Constantin   gabriela.constantin_at_univr.it    Link

Gabriela Constantin, MD, PhD is a Professor of General Pathology and Immunology and Head of the Laboratory of Neuroimmunology at the University of Verona, Italy. Dr. Constantin received her medical degree and completed her residency in neurology at the University of Milan, Italy. She obtained a PhD in molecular and cellular pathology at the University of Verona. She is a recognized leader in neuroimmunology and her studies are focused on the role of leukocyte trafficking in brain autoimmune and inflammatory diseases. She contributed to the identification of key inflammation mechanisms in multiple sclerosis, epilepsy and Alzheimer's disease. Dr. Constantin's group is also particularly interested in characterizing the biological networks controlling T cell activation, inflammation and autoimmunity. Her projects are funded by national and international agencies including the European Research Council (ERC), National Multiple Sclerosis Society (NMSS) NY, USA, Alzheimer's Drug Discovery Foundation (ADDF) USA and Fondazione Italiana Sclerosi Multipla (FISM), Genoa, Italy. Lab website: dp.univr.it/~constantin/LONI



Prof. Lucia De Franceschi   lucia.defranceschi_at_univr.it    Link

Biosketch



Dr. Daniele Dell'Orco   daniele.dellorco_at_univr.it    Link

Daniele Dell'Orco studied Physics and Biophysics at the University of Parma (Italy) and Lund (Sweden). He obtained a PhD in Biotechnology and Molecular Medicine from the University of Modena and Reggio Emilia (Italy). During his pre- and post-doctoral activity he visited several laboratories in Sweden and in Germany, to gain expertise in computational and experimental biophysical chemistry and systems biology. He has been A. von Humboldt Research Fellow at the University of Oldenburg (Germany) for almost 2.5 years. Since December 2011 he is Assistant Professor at the University of Verona, at the Biological Chemistry section of the Medical Faculty. He is also Adjunct Professor of Bioinformatics at the Natural Sciences Faculty of the same University. On a regular basis Dr. Dell'Orco acts as a referee for several peer-review journals in the fields of Biochemistry, Biophysical Chemistry, Systems Biology and Biomaterials. He is a member of the Biochemical Society (UK), the Italian society of Biochemistry and Molecular Biology (SIB) and the Bioinformatics Italian Society (BITS). Research interests: Dr. Dell'Orco's scientific activity is focused on the experimental and theoretical characterization of protein-protein and protein-ion interactions involved in vertebrate vision. This includes systems biology approaches to unravel the biochemical mechanisms behind complex cell behaviors in photoreceptors during normal and disease-associated conditions. He uses a number of experimental biophysical techniques such as Surface Plasmon Resonance, Isothermal Titration Calorimetry, Circular Dichroism, Fluorescence and Absorption spectrometries, in order to characterize the (thermo)dynamics and the kinetics of the processes under investigation. This allows him to obtain kinetic and thermodynamic constants that can then be employed in mathematical models. Daniele is also active in computational structural biology especially in the fast semi-empirical characterization of protein-protein interactions in normal and in disease-associated conditions by means of molecular simulation and docking algorithms, and bioinformatics techniques. More recently, Dr. Dell'Orco became involved in the computational analysis of nanoparticle-protein interactions in several biologic fluids and the perturbations exerted by nanoparticle-protein complexes on biochemical processes.



Dr. Michele Ettorre   michele.ettorre_at_univr.it    Link

Ettorre Michele graduated in Pharmaceutical Chemistry and Technology at the University of Padova with a thesis about synthesis, characterization an biological activity of a new metallorganic complex of Pt(II). In 2009 he received, from Verona University, a Ph.D. in Neuroscience, discussing a thesis entitled “Electrophysiological and morphological characterization of glutamatergic synapses in mammalian skeletal muscle”. His research interests are focused on the the molecular mechanisms underlying the axonal regeneration in the central and peripheral nervous system; mechanisms that regulate the development of synapses in the peripheral and central nervous system; and proprierties of the chloride channel CFTR, whose disfunction underlies cystic fibrosis disorder. He is currently working, as a Research Associate, on the effects of Rho GTPases in the neuronal survival and regeneration after injury. His expertises involve electrophysiological (patch clamp in whole cell configuration) and imaging (multiphoton microscopy; confocal microscopy; fluorescence microscopy) techniques. He is co-author of several peer-reviewed journal articles and conference acts.



Dr. Alessandro Farinelli   alessandro.farinelli_at_univr.it    Link

Alessandro Farinelli is a researcher at University of Verona, Department of Computer Science, since December 2008. In 2005 he received the PhD in Ingegneria Informatica (Computer Science) at Dipartimento Informatica e Sistemistica (DIS) Università di Roma "La Sapienza" (Advisor: Prof. Daniele Nardi). He participated in several national and international research projects. In particular, in 2003 he was a research visitor of the TEAMWORK research group headed by Prof. Milind Tambe at the University of Southern California, and from 2007 to 2009 he was a research fellow in the agents group headed by Prof. Nick Jennings at the University of Southampton. His research interests comprise theoretical and practical issues related to the development of Artificial Intelligent Systems. In particular, he focuses on the application of various techniques (such as optimization and patter recognition) to analyze complex systems (such as biological processes).



Dr. Giuditta Franco   giuditta.franco_at_univr.it    Link

Giuditta Franco graduated in Mathematics from the University of Pisa and earned her PhD in Computer Science, with a dissertation entitled `Biomolecular Computing---Combinatorial Algorithms and Laboratory Experiments', at the University of Verona, where she currently holds a permanent research position (ricercatore). Her research interests lie between discrete mathematics and theoretical computer science, with a focus on computational models of biological systems and on biomolecular computing, in particular Membrane and DNA computing. Her work involves informational analysis of DNA sequences as well as dynamic modelling, by means of membrane systems, of immunological processes and of cellular tissue healing. The results of her analytical and experimental (in molecular biology laboratories) study of biomolecular algorithms include: novel methods of DNA extraction and recombination; the discovery of informational and computational principles characterizing DNA molecular structure; and new theoretical models for the generation of DNA three-dimensional structures via self-assembly. Dr Franco spent several periods abroad, specifically in the United States (at the University of South Florida and at the SUNY Binghamton) and in the Netherlands (at the Leiden Institute of Advanced Computer Science). She has given talks in numerous international workshops and has been on the program committee for various conferences. She is a co-author of several scientific papers, which have appeared in prestigious international journals (such as Mathematical Biosciences, TCS, Natural Computing, Biosystems, The Journal of Logic and Algebraic Programming), and is a reviewer for several international journals, including journals of the American Mathematical Society. She is currently a member of both the European Molecular Computing Consortium (EMCC) and the International Society for Nanoscale Science, Computing and Engineering (ISNSCE).



Dr. Alejandro Giorgetti   alejandro.giorgetti_at_univr.it    Link

Dr. Alejandro Giorgetti has been appointed as Assistant Professor of Biochemistry at the University of Verona, Italy since 2007. Since his appointment, he is the Principal Investigator of the Applied Bioinformatics Group. The main research interests of the group include: protein modelling from sequence, in particular using comparative modelling techniques; protein structure analysis; protein sequence analysis; protein design; and the development of tools aimed at the investigation and understanding of the relationship between protein sequence, structure and function. The group is actively involved in different collaboration projects both within the national territory and with scientists abroad. Recently he has been also appointed as Adjunct Visiting scientist (2011-2014) at the German Research School for Simulation Sciences (GRS), Juelich, Germany.



Prof. Carlo Laudanna   carlo.laudanna_at_univr.it    Link

Prof. Carlo Laudanna was born in Milan, Italy, the 12/10/1962. At the University of Verona, he received the doctoral degree in Medicine at Surgery in 1988, and the PhD in Cellular and Molecular Biology and Pathology in 1995. He is associate professor of General Pathology. From June 1993 to July 1997 he was in the laboratory of Prof. Eugene C. Butcher, Stanford University, CA, USA, where he started studies regarding the molecular mechanisms regulating lymphocyte adhesion and migration by chemotactic factors, either in in vitro as well as in in vivo models. Prof. Laudanna main scientific activity regards the characterization of intracellular signaling mechanisms involved in the regulation of leukocyte recruitment under physio-pathological conditions; in this field he is author of several articles and reviews concerning regulation of integrin activation by signaling mechanism triggered in leukocytes by chemotactic factors. Prof. Laudanna is also supported by Italian Association for Cancer Research (AIRC) to study the signaling mechanisms controlling integrin triggering and mediated adhesion in neoplastic B- and T-lymphocytes isolated from CLL patients. Prof. Laudanna laboratory has developed several technologies to study integrin triggering and signaling mechanisms under physiological conditions, including the development of Trojan peptide technologies to study the role of mutated signaling proteins and of protein domains in the regulation of specific signaling pathways leading to adhesion and motility in mouse and human primary leukocytes without the need of DNA transfection. This technology is systematically coupled to intravital microscopy, developed at the University of Verona by dr. G. Constantin group, to accomplish a physiological analysis of signaling mechanisms involved in the regulation of lymphocyte homing in secondary lymphoid organs and of autoreactive lymphocytes in inflamed tissues. The increasing complexity of intracellular signaling networks regulating cell functions prompted the interest of prof. Laudanna for the principles and methods of Systems Biology. Prof. Laudanna is co-founder and President of the Center for BioMedical Computing, CBMC. The CBMC is an interdisciplinary joint initiative between the faculties of Medicine and of Science of the University of Verona. Its goal is to develop mathematical theories allowing abstraction and analysis of the topology and dynamics of intracellular signaling networks and, more in general, of biological networks, with particular focus on clinically relevant applications. The CBMC is fully supported by Fondazione Cariverona.



Dr. Zsuzsanna Lipták   zsuzsanna.liptak_at_univr.it    Link

Zsuzsanna Lipták got her first degree in mathematics from Freie Universität Berlin in 1999. She did her PhD studies at ETH Zurich, Switzerland (1999-2003), and Bielefeld University, Germany (2003-2005), where she defended her thesis on "Strings in Proteomics and Transcriptomics: Algorithmic and Combinatorial Questions in Mass Spectrometry and EST Clustering" in July 2005. She then worked as a postdoctoral researcher at the Genome Informatics research group at Bielefeld University. She was a visiting scientist, in 2002 and 2003, at the South African National Bioinformatics Institute (SANBI) in Cape Town and at the University of the Witwatersrand, Johannesburg, South Africa, working on gene expression (EST clustering). She was visiting scientist at the Rényi Institute of Mathematics, Budapest (Hungarian Academy of Sciences), in 2009 and 2010, working on string reconstruction within the EU-funded FP7-project "Hungarian Bioinformatics." In 2011, she received a Marie Curie Intra-European Fellowship from the European Union (FP7), for an individual research project at the University of Salerno, Italy, on theory and applications of jumbled string matching in bioinformatics. Since Nov. 2011, she has been assistant professor at the University of Verona. Her research lies in the area of algorithmic bioinformatics, focussing on algorithmic and combinatorial problems arising in bioinformatics applications, with particular interest in problems on biological sequences (also called strings). She has worked extensively on algorithms for identification of biomolecules from mass spectrometric data, on clustering algorithms for gene expression data, and, more recently, on applications to bioinformatics of non-conventional string matching algorithms. Her work is published in high-level international journals and conferences both in the area of bioinformatics (Bioinformatics, Journal of Proteome Research, WABI, IEEE-BIBE), and in the area of algorithms (Algorithmica, Journal of Discrete Algorithms, Discrete Applied Mathematics, COCOON, ACM SAC, CPM).



Dr. Rosario Lombardo   rosario.lombardo_at_univr.it    Link

 Rosario Lombardo graduated cum laude in Computer Science (2008) at the University of Pisa and received his Ph.D. in Bioinformatics (2013) from the University of Verona defending the thesis "Unconventional Computations and Genome Representations".

In 2012 he joined the Section of Psychiatry of the Verona Hospital where he inferred regulatory networks and biomolecular pathways associated with psychiatric complex diseases working on clinical and genetic data. In 2013 he joined as researcher The Microsoft Research - University of Trento Centre for Computational and Systems Biology (COSBI) where he has focused on the development of new techniques for inferring structure and parameters of biological networks from biological omics data.

Previously, from 2005 to 2007, Rosario was a research associate at the Institute of Science and Technology of Information (ISTI), National Research Council (CNR) of Pisa within the National e-Science project ESCOGITARE where he designed and deployed bioinformatics workflows over the Grid in the field of plant genetics and established and maintained the CNR's AccessGrid node, a distributed, highly-interactive, collaborative environment over the internet. In 2004 Rosario was assistant professor at the Computer Science dept. of the University of Pisa. Earlier in Pisa he was awarded grants at the Institute of Information and Telecommunications (IIT-CNR) and in 2003, during his B.Sc., he spent 7 months at the Linköping Universitet (Sweden) where he developed machine learning, AI methods and optimization algorithms for Situated Multi-Agent systems.

From 2008 to 2013 he was Project Manager and Senior Consultant in Unicredit Group’s cross-country financial and banking ICT programs covering Italy, Germany, Austria and the Eastern EU countries where the Group is present. Rosario's industry-level consultancy expertise ranges from Program governance, IT strategy and Change Management to budgeting, personnel and activity management across multi-country programs.
Since ever Rosario has been a technology enthusiast and a freelance web-designer focused on providing rich end-user experiences through high usability standards.



Prof. Vincenzo Manca   vincenzo.manca_at_univr.it    Link

Vincenzo Manca is a Full Professor, since 2002, at the Computer Science Department of the University of Verona. He obtained his degrees from the University of Pisa, under the guide of Alfonso Caracciolo di Forino and Ennio De Giorgi, where he became Assistant Professor in 1980. E' was Associate Professor at the Universities of Udine and Pisa. His research interests cover a wide class of topics from mathematical logic, discrete mathematics, and theoretical computer science, to informational analysis and computational models of biological systems. At present, his investigation is focused on "Computational Systems Biology" and "Natural Computing". In 2004 he introduced MP grammars as a mathematical methodology for deducing discrete models of biological dynamics. He is author of more than 170 scientific publications, appearing in international journals and scientific series. Recently he published the book "infobiotics: information in biotic systems (V. Manca, Springer, Berlin - Heidelberg, 2013). He is reviewer for Mathematical Reviews and also referee for many scientific journals and conferences, has been member of Program Committee of many important international conferences and was visiting professor and "invited speaker" in many universities and international conferences. He is member of E.M.C.C. (European Molecular Computing Consortium) and directed several research projects in the field of natural computing, collaborating actively with several international research groups. He has advised 7 Ph.D students, and tutored more than 40 M.Sc. students. He was co-founder and president of the Programme in Bioinformatics, at the University of Verona (the Faculty of Sciences). Since October 2012 he is president of CBMC.



Dr. Luca Marchetti   luca.marchetti_at_univr.it   

Luca Marchetti graduated in Computer Science and earned his PhD in Computer Science at the University of Verona in 2012. Actually, he is post-doc research associate at the "Computational BioMedical Center" (CBMC) of the University of Verona. His research interests are mainly focused on Systems Biology, Natural Computing and, more specifically, on algorithmic biological modelling (P systems and MP systems). Recently, he defined, with Prof. Vincenzo Manca, the Log-Gain Stoichiometric Stepwise regression algorithm (LGSS) for the analysis of biological dynamics. He is involved in many international projects on computational models of biomedical phenomena (Karmanos Cancer institut, Detroit - USA, National Institute of Biology- Department of Biotechnolog and Systems Biology, Ljubljana - Slovenia, Faculty of Life Sciences, The University of Manchester - UK, Endocrinology Diabetes models, Endocrinology Section at the Department of Medicine, Un. Verona). He is author of 12 scientific papers (5 Int. Journals, 4 Vol. Chapters, 2 Conf. Proceedings) and presented talks to 10 international conferences. Presently, he is developing a computational integrated computational platform yielding tools for design, simulation, and analysis of MP models and for their integration with platforms and formalisms that are standard in Systems biology.



Prof. Gloria Menegaz   gloria.menegaz_at_univr.it    Link

Gloria Menegaz was born in Verbania, Italy. She graduated in Electronic Engineering at the Politecnico di Milano in July 1993 and obtained a post-grade MSc in Information Technology from the CEFRIEL-Politecnico di Milano in 1995. In fall 1995 she joined the Signal Processing Institute (ITS) of the Swiss Federal Institute of Technology (EPFL) where she got the PhD in applied sciences in July 2000. From 2000 to 2002 she was first assistant at the Audiovisual Communications Lab. (LCAV) at EPFL, and from 2002 to 2004 she was Assistant Professor at the Computer Science Dept. of the University of Fribourg (Switzerland). From 2004 to 2007 she was an Adjunct Professor the Dept. of Information Engineering at the University of Siena thanks to the Rientro dei Cervelli grant (DM 20/03/2003, n. 501). Since October 2007 she is Associate Professor at the Dept. of Computer Science of the University of Verona. In July 2005, Jan. 2007, June 2008, Sept. 2009, June 2010 and 2011 she was invited Professor at the University of Aix-Marseille III, France. She serves as Independent expert the European Commission, appointed by the DG for Research, the DG for INFSO, the European Spatial Agency (ESA) and the European Research Council (ERC), for the Swedish Knowledge Foundation, the Agence Nationale de Recherche, France and the Italian Ministry for University and Research. She is qualified as Professor (Professeur des Universités) in the French academic system in the Section of Computer Science (Sections 27). She is Associate Editor of the EURASIP J. of Advances in Signal Processing and J. of Video Technology. She published more than eighty papers in peer-reviewed international journals and proceedings of international conferences, and she contributed to the JPEG2000 and MPEG4 standards. Her research activity is in the field of human brain mapping, neuroimaging and visual perception.



Dr. Alessio Montresor   alessio.montresor_at_univr.it    Link

Alessio Montresor graduated in Biology at the University of Padova in 2004 and earned his PhD in Molecular and Cellular Biology and Pathology in 2010, with a study focused to the investigation and characterization of signal transduction mechanisms in B-lymphocytes from healthy donors and B-CLL (B-lymphocytes chronic lymphocytic leukemia) patients, at the Department of Pathology and Diagnostics, at the University of Verona, where he currently works. His studies are focused on signal transduction events in human lymphocytes, involved in proadhesive events, to better characterize the complex events activated and the hierarchy between identified members of protein signaling networks, already described. His work also focuses on the phosphoproteomic analysis in several leukocytic cells to deeper describe the complex intracellular mechanisms, taking advantage of powerful bionformatic softwares, working in the CBMC. This phosphopreotemic service was also provided in collaboration for other research groups. His expertise also involves the ImageStream system, a powerful technology able to provide high-throughput information regarding biological features, such as morphology, cell shape, clusterization, signal transduction events, and more over. This technology is fully operative at the CBMC and it was applied for collaborations with other groups, and also for applicative demonstrations to increase the knowledge and the working opportunities of the instrument.



Prof. Romeo Rizzi   romeo.rizzi_at_univr.it    Link

Romeo Rizzi was born in 1967. He received the Laurea degree in Electronic Engineering from the Politecnico di Milano in 1991, and in 1997 received a Ph.D. in Computational Mathematics and Informatics from the University of Padova, Italy. Afterwards, he held Post-Doc and other temporary positions at research centers like CWI (Amsterdam, Holland), BRICS (Aarhus, Denmark) and IRST (Trento, Italy). In 2001, he became Assistant Professor at the University of Trento (INF/01). In 2005, he was called as Associate Professor by the University of Udine (MAT/09). Since 2012, he is still Associate Professor by the University of Verona (MAT/09). He has a background in Operations Research and his main interests are in Combinatorial Optimization and Algorithms. He is an Area Editor of 4OR and acts as a Reviewer for the American Mathematical Society. He has published more than 100 scientific papers with over 60 articles in a broad range of scientific journals in the areas of Discrete Mathematics, Combinatorics, and Algorithms. He has mainly contributed within the following broad subareas: Combinatorial Optimization, Graph Theory, Computational Biology, Approximation Algorithms, Parallel Architectures and Algorithms. Prior to entering academics, he has had teaching experiences in high schools of various profiles, ranging from commerce, to tech (ITIS), to lyceums. Even after entering academics, he kept on collaborating with highschools and Sovrintendenze Scolastiche (Trento and Bolzano) in initiatives related to the iOi (the olympics in informatics) at a local level. Since 2004, he has been a trainer of the Italian team for the iOi under commission from AICA. Nowadays, he collaborates with highschools in Trento, Bolzano, Udine, Bologna and Verona in initiatives related to the iOi. During his scientific career, he has opened and closed a few mathematical conjectures and has been a visitor in Vancouver (Canada), Victoria (Canada), Scherbrook (Canada), Grenoble (France), Paris (Orsay, France), Nice (France), and Newcastle (Australia).



Dr. Giovanni Scardoni   giovanni.scardoni_at_gmail.com    Link

Giovanni Scardoni graduated in Computer Science at the University of Verona and in 2010 he received, from the same University, a Ph.D. in Computer Science discussing a thesis entitled "Computational analysis of biological networks". His research activity is focused on network science, particularly the development and implementation of algorithms for extracting information from biological networks. He is currently working as a Research Fellow at the Center for BioMedical Computing (CBMC) in Verona. He developed several Cytoscape plugins: Pesca, for the shortest path betweenn nodes, Metabolica, a network motifs finder, and CentiScaPe a software for calculating network centralities and integrating network analysis with experimental data. He is author of journal articles and conference acts and gave talks in international workshops and conferences. At presents he is working on "centralities interference", a notion to measure how networks rearrange after nodes deletion and on the next release of the CentiScaPe plug-in.



Dr. Lara Toffali   lara.toffali_at_univr.it    Link

Dr. Lara Toffali has a degree in Molecular and Industrial Biotechniques at University of Verona. She is PhD student in “Molecular and Cellular Biology and Pathology” of the “Traslational Biomedicine School” at the Department of Pathology and Diagnostic, University of Verona, under the supervision of Prof. C. Laudanna. She is involved in projects concerning the study of signaling events regulating leukocyte trafficking. Specifically, she is expert in studying signaling events under flow conditions. She is the administrator of the BioFlux facility and provides service for computational analysis of cell interaction under flow.



Dr. Simone Zorzan   simone.zorzan_at_univr.it    Link

Simone Zorzan graduated in Computer Science at the University of Verona and in 2010 he received, from the same University, a Ph.D. title in Molecular, Industrial and Environmental Biotechnologies, discussing a thesis entitled “Protein-protein interaction dynamics in photosynthetic membrane: biochemical and in silico comparative analysis”. His research activity is focused on the development of applications and bioinformatic protocols for biological investigations. During his Ph.D. he worked on functional genomic (microarrays) data analysis, electron microscopy analysis tools, membrane proteins modeling and molecular dynamics. He collaborated with the group of Prof. Nicolas Le Novére at the European Bioinformatics Institute to the development of coarse-grained molecular dynamics software “Meredys” and to its application in the modeling of photosynthetic organism’s membrane dynamics. He is currently a Research Associate at the Center for BioMedical Computation (CBMC) in Verona and his activity is focused on the bioinformatic study of the mechanisms of neuronal plasticity, Alzheimer and B-Cell Chronic Lymphocytic Leukemia through antibodies microarrays analyses. He is also active in the development of bioinformatic tools like HOMECAT for orthologs and functional genomic comparative data integration. Simone is Adjunct professor for the Bioinformatics Laboratory I, Bioinformatics and Biotechnology Bachelor Programs and co-author of several peer-reviewed journal articles and conference acts.